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Symbol
Name
ID
Igf1r
insulin-like growth factor I receptor
MGI:96433
Phenotype annotations related to immune system
Darker colors indicate more annotations
Human Phenotypes
Lymphadenopathy
Hepatosplenomegaly
Peritoneal abscess
Subacute progressive viral hepatitis
Nephritis
Disease(s) Associated with IGF1R
hepatocellular carcinoma
IgA glomerulonephritis
neuroblastoma
pancreatic cancer

Mouse Phenotypes
decreased osteoclast cell number
abnormal osteoclast physiology
decreased susceptibility to type I hypersensitivity reaction
Availability Mouse Genotype
Igf1rtm1Jcbr/Igf1rtm1Jcbr
Ndor1Tg(UBC-cre/ERT2)1Ejb/0  (conditional)
Igf1rtm2Arge/Igf1rtm2Arge
Tg(BGLAP-cre)1Clem/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory